Pattern of Oral and Maxillofacial Biopsy Results in a Teaching Hospital; An 11-year Retrospective Study
Abstract
Background
Biopsy remains a cornerstone in diagnostic pathology, enabling definitive diagnosis, guiding treatment planning, and informing tumor classification. This study evaluated the distribution of histopathologically diagnosed lesions in the oral and maxillofacial region over an 11-year period.
Methods
 A retrospective review was conducted at the Department of Oral and Maxillofacial Surgery, Oral Pathology, and Molecular Biology, Lagos University Teaching Hospital, Nigeria. Biopsy records from January 2013 to December 2023 were analyzed. Ethical approval was obtained from the Health Research and Ethics Committee (HREC Approval No. ADM/DSCST/HREC/APP/5714).
Results
 A total of 756 biopsies were reviewed. Females accounted for 52.2% of cases. The highest frequency of tumors occurred in the fourth decade of life (20.8%). Odontogenic tumors were the most prevalent lesion group, with ameloblastoma being the most common histologic diagnosis, predominantly involving the mandible.
Conclusion
A broad spectrum of lesions affects the maxillofacial region. Biopsy remains indispensable for definitive diagnosis. Knowledge of lesion distribution patterns is vital for clinical decision-making among oral surgeons and pathologists.
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Keywords (MeSH)
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References
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